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By Dr. Sehba Asim Nehal in Internal Medicine
Jul 22 , 2024 | 6 min read
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A Complete Blood Count (CBC) test is one of the most common and informative diagnostic tools in modern medicine. By analysing various components of your blood, a CBC test can reveal a wealth of information about your overall health. Most people, however, are unable to understand their CBC test results and interpret what their blood tells them about their body's functioning and potential health issues. That’s why in this article, we’ll explore the key components of a CBC test, what the results mean, and how they can provide valuable insights into your health. Let’s begin.
What is a Complete Blood Count test?
A Complete Blood Count is a routine blood test that provides a detailed overview of your blood's components. It is often used as a screening tool to assess overall health and diagnose various medical conditions. By examining different elements of your blood, a CBC helps healthcare providers understand your body's overall health and detect potential abnormalities.
When is a CBC Test Prescribed by a Doctor?
A Complete Blood Count is a versatile diagnostic tool used to help in the diagnosis of a variety of medical conditions. Here are common scenarios when a CBC blood test might be used:
- Routine health check-up: Regular health check-ups often include a CBC to monitor your overall health and screen for potential health issues before they become serious.
- Symptoms of infection: If you exhibit symptoms such as fever, chills, fatigue, or signs of an infection, a CBC can help determine if an infection is present and whether it is bacterial or viral in nature.
- Symptoms of anaemia: Symptoms such as persistent fatigue, weakness, shortness of breath, or pale skin may prompt a CBC to check for anaemia and identify the type and severity.
- Unexplained bruising or bleeding: A CBC can help investigate unexplained bruising, bleeding, or frequent nosebleeds by evaluating platelet levels and function.
- Monitoring chronic conditions: For individuals with chronic conditions such as kidney disease, autoimmune disorders, or cardiovascular diseases, a CBC can help monitor the condition and the effectiveness of treatments.
- Pre-surgery evaluation: Before undergoing surgery, a CBC is often performed to ensure that you are healthy enough for the procedure and to check whether you need transfusion of blood or blood products and to check for any underlying issues that could complicate the surgery.
- Diagnosing blood disorders: If you have symptoms suggestive of blood disorders, such as frequent infections, unusual bleeding, or fatigue, a CBC can help diagnose conditions like low platelet disorders, polycythemia, leukaemia, lymphoma, or other blood-related illnesses.
- Monitoring medication effects: Certain medications, such as chemotherapy drugs, can affect blood cell counts. A CBC helps monitor these effects and guide adjustments in treatment.
- Pregnancy: During pregnancy, a CBC is routinely performed to monitor the health of both the mother and the developing foetus, checking for conditions like aplastic anaemia or infections.
- Fatigue and weakness: Persistent fatigue and weakness that do not have an obvious cause can be investigated with a CBC to check for underlying issues like anaemia or infections.
- Evaluation of immune function: A CBC can help evaluate immune function by assessing white blood cell counts, which is particularly useful in patients with immune system disorders or those undergoing treatments like immunosuppressive therapy.
Which Components are Measured by a CBC Test?
A Complete Blood Count test is used to measure various components of blood. Here are the components of blood it measures, along with their normal range and application in diagnosis:
1. Red Blood Cells (RBCs)
The CBC test reveals various aspects of the RBC in the blood, including:
- Haemoglobin (Hb): Measures the amount of haemoglobin in the blood. Haemoglobin is the protein in red blood cells that carries oxygen.
- Normal range:
- Men: 13.8 to 17.2 grams per deciliter (g/dL)
- Women: 12.1 to 15.1 grams per deciliter (g/dL)
- Low haemoglobin levels can indicate anaemia, while high levels can suggest polycythemia or other conditions.
- RBC count: Measures the number of red blood cells in a specific volume of blood.
- Normal range:
- Men: 4.7 to 6.1 million cells per microliter (cells/µL)
- Women: 4.2 to 5.4 million cells per microliter (cells/µL)
- Abnormal RBC counts can indicate conditions such as anaemia, dehydration, or polycythemia.
- Hematocrit (Hct): Measures the proportion of blood volume occupied by red blood cells.
- Normal range:
- Men: 40.7% to 50.3%
- Women: 36.1% to 44.3%
- The hematocrit value helps in diagnosing and evaluating the severity of anaemia or polycythemia.
2. White Blood Cells (WBCs)
The CBC test is also used to measure the number of white blood cells in a specific volume of blood. The normal range of WBCs in blood is 4,500 to 11,000 cells per microliter (cells/µL). If the result shows an elevated WBC, it may indicate an infection, inflammation, or leukaemia. A low WBC count, on the other hand, could be due to viral infections, bone marrow problems, autoimmune disorders, or certain medications.
3. Platelets
The CBC test also provides the number of platelets in a specific volume of blood. The normal range of platelets is 150,000 to 450,000 platelets per microliter (platelets/µL). A very low platelet count (thrombocytopenia) can lead to excessive bleeding and bruising, while a high platelet count (thrombocytosis) can increase the risk of clotting disorders. Low platelet count can be caused by certain infectious blood disorders, medications, etc.
4. Mean Corpuscular Volume (MCV)
The MCV is a measure of the average size of red blood cells, and a normal MCV can range from 80 to 100 femtoliters (fL). The MCV value helps in diagnosing different types of anaemia. Low MCV (microcytic anaemia) can indicate iron deficiency anaemia or thalassemia, while high MCV (macrocytic anaemia) can be caused by vitamin B12 or folate deficiency, chronic liver disease, or alcoholism.
How is the Complete Blood Count Test Performed?
The Complete Blood Count (CBC) test is a straightforward procedure, from collecting the blood sample to analysing it in a laboratory. Here’s how the process typically works:
1. Blood sample collection
For adults and older children
- Preparation: Usually, no special preparation is needed for a CBC test. However, your healthcare provider may give specific instructions if other tests are being done simultaneously.
- Procedure:
- Site selection: A healthcare staff will select a vein, usually in the arm, for drawing blood.
- Cleaning: The skin over the vein is cleaned with an antiseptic to prevent infection.
- Tourniquet application: A tourniquet (a tight band) is placed around the upper arm to fill the vein with blood, making it easier to draw.
- Blood draw: A sterile needle is inserted into the vein, and blood is collected into a vial or syringe. The process typically takes a few minutes.
- Post-procedure: After the blood is drawn, the needle is removed, and a bandage is applied to the puncture site. You might be asked to apply pressure for a few minutes to stop any bleeding.
For infants
- Heel prick: For newborns and very young infants, a small sample of blood is often collected through a heel prick. This involves:
- Warming the Heel: The infant's heel may be warmed to increase blood flow.
- Cleaning: The heel is cleaned with an antiseptic.
- Prick: A small, sterile lancet is used to make a tiny puncture in the heel.
- Blood collection: Blood is collected in a small tube or on a test strip. Pressure is then applied to the site to stop the bleeding, and a bandage is placed over the puncture.
2. Laboratory analysis
- The collected blood sample is labelled with the patient’s information and sent to a laboratory for analysis, where a series of tests are performed.
Note: In infants, especially newborns, CBC testing might be performed to check for infections, anaemia, or other conditions that can affect newborns. The process for infants generally involves less blood and special handling to ensure the sample is sufficient for accurate testing. In addition, efforts are made to minimise discomfort, and the procedure is generally quick. Parents or caregivers may be present to comfort the infant during the process.
Final words
Whether you're experiencing symptoms that concern you or simply undergoing a routine health check-up, a CBC can provide valuable information about your body's functioning. If you have questions about your CBC results or need further evaluation, book a consultation with a specialist at Max Hospitals today. Placed among the leading hospitals in India, Max Hospitals offer comprehensive diagnostic services and expert medical care. Reach out to a specialist at Max Hospitals and put yourself on the path to optimal health and well-being.
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